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Vosevi Dosage

Generic name: sofosbuvir, velpatasvir, and voxilaprevir
Drug class: Antiviral combinations

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  TAB: 400 mg/100 mg/100 mg

Chronic hepatitis C infection, genotypes 1-6

[pts w/o cirrhosis or w/ compensated cirrhosis]
Dose: 1 tab PO qd x12wk; Info: may give w/ ribavirin; may give x24wk; refer to AASLD/IDSA hepatitis C guidelines; give w/ food

Renal dosing

[no adjustment]
renal impairment: no adjustment
HD/PD: no adjustment; no supplement

Hepatic dosing

Child-Pugh Class B or C: avoid use



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