Vonjo Dosage

Generic Name Pacritinib
Dosage Form Capsules

 

 Recommended Adult Dosing

Dosage forms:  CAP: 100 mg

Special Note

[uses, dosing may vary]
Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

Myelofibrosis, intermediate or high-risk

[200 mg PO bid]
Info: for pts w/ primary or secondary dz and Plt <50,000; D/C other kinase inhibitors before tx start; D/C x7 days before elective surgery or invasive procedure; do not open/crush/chew cap

Renal dosing

eGFR <30: avoid use
HD: avoid use; PD: not defined

Hepatic dosing

Child-Pugh Class B or C: avoid use

SRC: NLM .