Vonjo Dosage
Generic Name Pacritinib
Dosage Form Capsules
Recommended Adult Dosing
Dosage forms: CAP: 100 mg
Special Note
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments
Myelofibrosis, intermediate or high-risk
- [200 mg PO bid]
- Info: for pts w/ primary or secondary dz and Plt <50,000; D/C other kinase inhibitors before tx start; D/C x7 days before elective surgery or invasive procedure; do not open/crush/chew cap
Renal dosing
- eGFR <30: avoid use
- HD: avoid use; PD: not defined
Hepatic dosing
- Child-Pugh Class B or C: avoid use
SRC: NLM .