Vocabria Dosage

Generic name: cabotegravir
Drug class: Integrase strand transfer inhibitor

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  TAB: 30 mg

HIV infection

[lead-in dosing w/ PO rilpivirine]

Dose: 30 mg PO qd for at least 28 days; Start: 1mo before cabotegravir and rilpivirine injections; Info: for short-term tx in pts w/ HIV-1 RNA <50 and no known tx failure or resistance to cabotegravir or rilpivirine; give w/ meals

[replacement dosing for missed cabotegravir and rilpivirine injections]

Dose: 30 mg PO qd until next cabotegravir and rilpivirine injections for up to 2mo; Start: 1-2mo after last cabotegravir and rilpivirine injections; Info: for short-term tx if planned missed cabotegravir and rilpivirine injections by >7 days; give w/ PO rilpivirine; give w/ meals

HIV pre-exposure prophylaxis

[lead-in dosing]

Dose: 30 mg PO qd for at least 28 days; Start: 1mo before cabotegravir injection; Info: for short-term use in at-risk pts; give w/ meals

[replacement dosing for missed cabotegravir injections]

Dose: 30 mg PO qd until next cabotegravir injection for up to 2mo; Start: 2mo after last cabotegravir injection; Info: for short-term use if planned missed cabotegravir injection by >7 days; give w/ meals

Renal dosing

renal impairment: no adjustment

HD/PD: not defined

Hepatic dosing

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined

SRC: NLM .