Vibativ Dosage

Generic name: telavancin
Drug class: Glycopeptide antibiotics

Medically reviewed by A Ras MD.

Recommended Adult Dosing

Dosage forms: INJ

[10 mg/kg/dose IV q24h x7-14 days]

Info: duration varies by infection site/severity

[10 mg/kg/dose IV q24h x7 days]

Info: may extend duration based on clinical response; refer to IDSA guidelines

[skin/skin structure infections]

CrCl 30-50: 7.5 mg/kg/dose q24h; CrCl 10-29: 10 mg/kg/dose q48h; CrCl <10: not defined; Info: decr. efficacy in pts w/ CrCl <50

HD: consider 10 mg/kg/dose q48h or 10 mg/kg/dose 3x/wk after dialysis; no supplement; PD: not defined; Info: decr. efficacy in pts w/ CrCl <50

[pneumonia]

CrCl 30-50: 7.5 mg/kg/dose q24h; CrCl 10-29: 10 mg/kg/dose q48h; CrCl <10: not defined; Info: weigh risk/benefit if CrCl <50

HD: consider 10 mg/kg/dose q48h or 10 mg/kg/dose 3x/wk after dialysis; no supplement; PD: not defined; Info: weigh risk/benefit if CrCl <50

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined

SRC: NLM .