Varubi Dosage

Generic name: rolapitant (oral – tablets)
Drug class: NK1 receptor antagonists

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  TAB: 90 mg

Nausea/vomiting prevention, chemo-related

[180 mg PO x1]
Start: 2h before moderately or highly emetogenic chemo on day 1; Info: give w/ corticosteroid and 5-HT3 antagonist

Renal dosing

CrCl >30: no adjustment; CrCl <30: not defined
HD/PD: not defined

Hepatic dosing

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined

 

SRC: NLM .