Varubi Dosage
Generic name: rolapitant (oral – tablets)
Drug class: NK1 receptor antagonists
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: TAB: 90 mg
Nausea/vomiting prevention, chemo-related
- [180 mg PO x1]
- Start: 2h before moderately or highly emetogenic chemo on day 1; Info: give w/ corticosteroid and 5-HT3 antagonist
Renal dosing
- CrCl >30: no adjustment; CrCl <30: not defined
- HD/PD: not defined
Hepatic dosing
- Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined
SRC: NLM .