Vancocin Dosage

Generic name: Vancomycin Capsules
Drug class: Glycopeptide antibiotics

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  CAP: 125 mg, 250 mg

C. difficile infection

[*non-fulminant]
Dose: 125 mg PO q6h x10 days; Info: for 1st episode
[*fulminant]
Dose: 500 mg PO/NG q6h; Info: 1st-line agent; may give w/ metronidazole IV; consider adding vancomycin 500 mg in 100 mL NS retention enema PR q6h if complete ileus
[*1st recurrence]
Dose: 125 mg PO q6h x10-14 days, then 125 mg PO q12h x7 days, then 125 mg PO qd x7 days, then 125 mg PO q2-3 days x2-8wk; Info: may give 125 mg PO q6h x10 days if metronidazole initial regimen
[*2 or more recurrences]
Dose: 125 mg PO q6h x10-14 days, then 125 mg PO q12h x7 days, then 125 mg PO qd x7 days, then 125 mg PO q2-3 days x2-8wk; Alt: 125 mg PO q6h x10 days, then rifaximin x20 days

Enterocolitis, staphylococcal

[500-2000 mg/day PO divided q6-8h x7-10 days]

Renal dosing

renal impairment: no adjustment; Info: consider monitoring serum levels if potential for systemic absorption
HD/PD: not defined

Hepatic dosing

[not defined]

 

SRC: NLM .