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Valcyte Dosage

Generic name: valganciclovir
Drug class: Purine nucleosides

Medically reviewed by  A Ras MD

 

 Recommended Adult Dosing

Dosage forms:  TAB: 450 mg; SOL: 50 mg per mL

CMV retinitis, AIDS-assoc.

[induction tx]
Dose: 900 mg PO bid x14-21 days; Info: give w/ food
[maintenance tx]
Dose: 900 mg PO qd; Info: give w/ food

CMV prophylaxis, heart transplant

[900 mg PO qd until 100 days post-transplant]
Start: w/ in 10 days of transplant; Info: give w/ food

CMV prophylaxis, kidney transplant

[900 mg PO qd until 200 days post-transplant]
Start: w/ in 10 days of transplant; Info: give w/ food

CMV prophylaxis, kidney-pancreas transplant

[900 mg PO qd until 100 days post-transplant]
Start: w/ in 10 days of transplant; Info: give w/ food

Renal dosing

[induction tx]
CrCl 40-59: 450 mg bid; CrCl 25-39: 450 mg qd; CrCl 10-24: 450 mg q48h; CrCl <10: avoid use
HD: 200 mg solution 3x/wk after dialysis; consider supplement if next maint. dose not due right after dialysis; PD: not defined
[prophylaxis or maintenance tx]
CrCl 40-59: 450 mg qd; CrCl 25-39: 450 mg q48h; CrCl 10-24: 450 mg 2x/wk; CrCl <10: avoid use
HD: 100 mg solution 3x/wk after dialysis; consider supplement if next maint. dose not due right after dialysis; PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .

 

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