Valcyte Dosage
Generic name: valganciclovir
Drug class: Purine nucleosides
Medically reviewed by A Ras MD
Recommended Adult Dosing
Dosage forms: TAB: 450 mg; SOL: 50 mg per mL
CMV retinitis, AIDS-assoc.
- [induction tx]
- Dose: 900 mg PO bid x14-21 days; Info: give w/ food
- [maintenance tx]
- Dose: 900 mg PO qd; Info: give w/ food
CMV prophylaxis, heart transplant
- [900 mg PO qd until 100 days post-transplant]
- Start: w/ in 10 days of transplant; Info: give w/ food
CMV prophylaxis, kidney transplant
- [900 mg PO qd until 200 days post-transplant]
- Start: w/ in 10 days of transplant; Info: give w/ food
CMV prophylaxis, kidney-pancreas transplant
- [900 mg PO qd until 100 days post-transplant]
- Start: w/ in 10 days of transplant; Info: give w/ food
Renal dosing
- [induction tx]
- CrCl 40-59: 450 mg bid; CrCl 25-39: 450 mg qd; CrCl 10-24: 450 mg q48h; CrCl <10: avoid use
- HD: 200 mg solution 3x/wk after dialysis; consider supplement if next maint. dose not due right after dialysis; PD: not defined
- [prophylaxis or maintenance tx]
- CrCl 40-59: 450 mg qd; CrCl 25-39: 450 mg q48h; CrCl 10-24: 450 mg 2x/wk; CrCl <10: avoid use
- HD: 100 mg solution 3x/wk after dialysis; consider supplement if next maint. dose not due right after dialysis; PD: not defined
Hepatic dosing
- [not defined]
SRC: NLM .