TNKase Dosage

Generic name: tenecteplase
Drug class: Thrombolytics

Medically reviewed by  A Ras MD

 

 Recommended Adult Dosing

Dosage forms:  INJ

STEMI

[<60 kg]
Dose: 30 mg IV x1
[60-69 kg]
Dose: 35 mg IV x1
[70-79 kg]
Dose: 40 mg IV x1
[80-89 kg]
Dose: 45 mg IV x1
[>90 kg]
Dose: 50 mg IV x1

Acute ischemic stroke

[0.25 mg/kg IV x1]
Start: ASAP w/in 4.5h of sx onset; Max: 25 mg; Info: for pts eligible for mechanical thrombectomy

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[not defined]
severe impairment: caution advised

SRC: NLM .