Tivdak Dosage

Generic name: tisotumab vedotin-tftv
Dosage form: lyophilized powder for injection, for intravenous use
Drug class: Miscellaneous antineoplastics

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  INJ

Special Note

[formulation clarification]
Info: nonproprietary name = tisotumab vedotin-tftv
[uses, dosing may vary]
Info: refer to institution protocols and pkg insert prior to prescribing for uses, premeds, postmeds, and dosing incl. toxicity-related dose adjustments

Cervical CA, recurrent or metastatic

[2 mg/kg/dose IV q3wk]
Max: 200 mg/dose; Info: see pkg insert for detailed eye care requirement before, during and after infusion

Renal dosing

CrCl >30: no adjustment; CrCl <30: not defined
HD/PD: not defined

Hepatic dosing

bilirubin 1.1-1.5x ULN and any AST: no adjustment; bilirubin >1.5x ULN or AST >3x ULN: avoid use

 

SRC: NLM .