Tivdak Dosage
Generic name: tisotumab vedotin-tftv
Dosage form: lyophilized powder for injection, for intravenous use
Drug class: Miscellaneous antineoplastics
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: INJ
Special Note
- [formulation clarification]
- Info: nonproprietary name = tisotumab vedotin-tftv
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses, premeds, postmeds, and dosing incl. toxicity-related dose adjustments
Cervical CA, recurrent or metastatic
- [2 mg/kg/dose IV q3wk]
- Max: 200 mg/dose; Info: see pkg insert for detailed eye care requirement before, during and after infusion
Renal dosing
- CrCl >30: no adjustment; CrCl <30: not defined
- HD/PD: not defined
Hepatic dosing
- bilirubin 1.1-1.5x ULN and any AST: no adjustment; bilirubin >1.5x ULN or AST >3x ULN: avoid use
SRC: NLM .