Tirosint Dosage

Generic name: Levothyroxine Capsules
Drug class: Thyroid drugs

Medically reviewed by A Ras MD.

Recommended Adult Dosing

Dosage forms: CAP: 13 mcg, 25 mcg, 50 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137 mcg, 150 mcg, 175 mcg, 200 mcg; SOL: 13 mcg/mL, 25 mcg/mL, 37.5 mcg/mL, 44 mcg/mL, 50 mcg/mL, 62.5 mcg/mL, 75 mcg/mL, 88 mcg/mL, 100 mcg/mL, 112 mcg/mL, 125 mcg/mL, 137 mcg/mL, 150 mcg/mL, 175 mcg/mL, 200 mcg/mL

Special Note

[thyroid product equivalencies]

Info: for product conversion purposes, 100 mcg levothyroxine = 25 mcg liothyronine = 60-65 mg thyroid (porcine) = 1 grain liotrix

Hypothyroidism

[50-200 mcg PO qd]

Start: 1.6 mcg/kg/dose PO qd, then adjust dose by 12.5-25 mcg/day q4-6wk; Max: 300 mcg/day; Info: adjust dose based on TFTs; start 12.5-25 mcg/day, then adjust dose by 12.5-25 mcg/day q2-4wk if severe dz; start 12.5-25 mcg/day, incr. dose by 12.5 mcg/day q6-8wk in elderly pts and pts w/ cardiac dz; dose adjustments may be needed during pregnancy and/or immed. postpartum; give on empty stomach

TSH suppression

[individualize dose PO qd]

Info: for pts w/ thyrotropin-dependent well-differentiated thyroid CA; adjust dose to suppress TSH to levels based on clinical status; dose adjustments may be needed during pregnancy and/or immed. postpartum; give on empty stomach

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing