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Tepmetko Dosage

Generic name: tepotinib
Dosage form: tablets, for oral use
Drug class: Multikinase inhibitors

Medically reviewed by  A Ras MD


 Recommended Adult Dosing

Dosage forms:  TAB: 225 mg

Special Note

[uses, dosing may vary]
Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

MET-positive non-small cell lung CA, metastatic

[450 mg PO qd]
Info: for tumors w/ mesenchymal-epithelial transition (MET) exon 14 skipping; give w/ food; do not cut/crush/chew tab

Renal dosing

[see below]
CrCl >30: no adjustment; CrCl <30: not defined

Hepatic dosing

Child-Pugh Class A and B: no adjustment; Child-Pugh Class C: not defined



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