Tepmetko Dosage
Generic name: tepotinib
Dosage form: tablets, for oral use
Drug class: Multikinase inhibitors
Medically reviewed by A Ras MD
Recommended Adult Dosing
Dosage forms: TAB: 225 mg
Special Note
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments
MET-positive non-small cell lung CA, metastatic
- [450 mg PO qd]
- Info: for tumors w/ mesenchymal-epithelial transition (MET) exon 14 skipping; give w/ food; do not cut/crush/chew tab
Renal dosing
- [see below]
- CrCl >30: no adjustment; CrCl <30: not defined
Hepatic dosing
- Child-Pugh Class A and B: no adjustment; Child-Pugh Class C: not defined
SRC: NLM .