Jump To

Tegsedi Dosage

Generic name: inotersen
Drug class: Miscellaneous metabolic agents

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  INJ (pre-filled syringe): 284 mg per 1.5 mL

Restricted Distribution in US

Polyneuropathy, hereditary transthyretin-mediated amyloidosis-assoc.

[284 mg SC qwk]
Info: vitamin A supplementation recommended; hold if Plt <100,000, urinary protein creatinine ratio >1000 mg/g, or eGFR decr. to <45, see pkg insert

Renal dosing

[see below]
eGFR 30-89: no adjustment; eGFR <30: not defined; Info: hold if eGFR decr. to <45 during tx
HD/PD: not defined

Hepatic dosing

mild impairment: no adjustment; mod-severe impairment: not defined



Read Next Article

PHP Code Snippets Powered By : XYZScripts.com