Talzenna Dosa

Generic name: talazoparib
Drug class: PARP inhibitors

Medically reviewed by  A Ras MD

 Recommended Adult Dosing

Dosage forms:  CAP: 0.25 mg, 0.5 mg, 0.75 mg, 1 mg

Special Note

[uses, dosing may vary]
Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

GBRCA-mutated HER2-negative breast CA, locally advanced or metastatic

[1 mg PO qd]
Info: do not open cap

Renal dosing

[adjust dose amount]
CrCl 30-59: 0.75 mg qd; CrCl 15-29: 0.5 mg qd; CrCl <15: not defined
HD/PD: not defined

Hepatic dosing

[no adjustment]

 

SRC: NLM .