Tagrisso Dosage

Generic name: osimertinib
Drug class: EGFR inhibitors

Medically reviewed by  A Ras MD.

 

 Recommended Adult Dosing

Dosage forms:  TAB: 40 mg, 80 mg

Special Note

[uses, dosing may vary]
Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

Non-small cell lung CA

[adjuvant tx]
Dose: 80 mg PO qd for up to 3y; Start: after tumor resection; Info: for pts w/ EGFR exon 19 deletions or exon 21 (L858R) substitution mutations
[metastatic dz, first-line tx]
Dose: 80 mg PO qd; Info: for pts w/ EGFR exon 19 deletions or exon 21 (L858R) substitution mutations
[metastatic dz, previously treated pts]
Dose: 80 mg PO qd; Info: for pts w/ EGFR T790M mutations

Renal dosing

CrCl >15: no adjustment; CrCl <15: not defined
HD/PD: not defined

Hepatic dosing

Child-Pugh Class A and B: no adjustment; Child-Pugh Class C: not defined

 

SRC: NLM .