Syndros Dosage

Generic name: dronabinol
Brand names: Marinol, Syndros
Drug class: Miscellaneous antiemetics

Medically reviewed by A Ras MD.

Recommended Adult Dosing

Dosage forms: SOL: 5 mg per mL

Anorexia/weight loss, AIDS-assoc.

[2.1-4.2 mg PO bid]

Start: 2.1 mg PO bid, may incr. by 2.1 mg/day gradually; Max: 16.8 mg/day; Info: give 1h before lunch and dinner; decr. to 2.1 mg PO qpm or qhs if start dose poorly tolerated; consider starting 2.1 mg PO qpm or qhs in elderly pts; taper dose gradually to D/C if prolonged, high-dose use

Chemo-related nausea/vomiting, refractory

[4.2 mg/m^2/dose PO q2-4h x4-6 doses/day]

Start: 4.2 mg/m^2/dose PO 1-3h before chemo, may incr. by 2.1 mg/m^2; Max: 12.6 mg/m^2/dose; Info: round dose to nearest 0.1 mg; give 1st dose >30min before meal, then give consistently w/ or w/o food; consider decr. to 2.1 mg/m^2/dose PO qd 1-3h before chemo if start dose poorly tolerated; consider starting 2.1 mg/m^2/dose PO qd 1-3h before chemo in elderly pts; taper dose gradually to D/C if prolonged, high-dose use

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing