Synagis Dosage

Generic name: palivizumab
Drug class: Immune globulins

Medically reviewed by  A Ras MD.

 

Recommended Peds Dosing

Dosage forms:  INJ: 50 mg per 0.5 mL, 100 mg per mL

RSV prophylaxis, high-risk pts

[<1 yo at start of RSV season]
Dose: 15 mg/kg/dose IM qmo; Start: before RSV season or ASAP if during season; Max: 5 doses/season; Info: for use in pts born <29 wk gestation, pts w/ CLD of prematurity, significant congenital heart dz, airway abnormalities or neuromuscular dz w/ impaired airway clearance, severe immunocompromise, CF w/ CLD or nutritional compromise, or undergoing cardiac transplantation during RSV season; give additional dose ASAP postop if undergoing cardiopulmonary bypass; D/C if hospitalized for breakthrough RSV
[1-2 yo at start of RSV season]
Dose: 15 mg/kg/dose IM qmo; Start: before RSV season or ASAP if during season; Max: 5 doses/season; Info: for use in pts w/ CLD of prematurity requiring medical support w/in 6mo of start of RSV season, severe immunocompromise, CF w/ manifestations of severe lung dz or weight for length <10th percentile, or undergoing cardiac transplantation during RSV season; give additional dose ASAP postop if undergoing cardiopulmonary bypass; D/C if hospitalized for breakthrough RSV

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .