Symlin Dosage

Generic name: pramlintide
Brand names: SymlinPen 120, SymlinPen 60
Drug class: Amylin analogs

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  INJ (SymlinPen 60 pen): 1500 mcg per 1.5 mL; INJ (SymlinPen 120 pen): 2700 mcg per 2.7 mL

Special Note

[prescribing info]
Info: use SymlinPen 60 pen for 15 mcg, 30 mcg, 45 mcg, 60 mcg doses; use SymlinPen 120 pen for 60 mcg, 120 mcg doses

Diabetes mellitus, type 1

[30-60 mcg SC qac]
Start: 15 mcg SC qac, then may incr. by 15 mcg/dose no more frequently than q3 days

Diabetes mellitus, type 2

[120 mcg SC qac]
Start: 60 mcg SC qac x3 days, then may incr. to 120 mcg SC qac; Info: use w/ insulin

Renal dosing

[see below]
CrCl >15: no adjustment; CrCl <15 or ESRD: not defined
HD/PD: not defined

Hepatic dosing

[no adjustment]

 

SRC: NLM .