Sutent Dosage
Generic name: sunitinib
Drug classes: Multikinase inhibitors, VEGF/VEGFR inhibitors
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: CAP: 12.5 mg, 25 mg, 37.5 mg, 50 mg
Gastrointestinal stromal tumor, previously treated
- [50 mg PO qd on days 1-28 of 42-day cycle]
- Info: for pts w/ dz progression on or intolerance to imatinib
Renal cell CA
- [adjuvant tx]
- Dose: 50 mg PO qd on days 1-28 of 42-day cycle; Info: for pts w/ high recurrence risk; give x9 cycles
- [advanced dz]
- Dose: 50 mg PO qd on days 1-28 of 42-day cycle
Pancreatic neuroendocrine tumors, unresectable locally advanced or metastatic
- [37.5 mg PO qd]
- Info: for pts w/ progressive, well-differentiated dz
Renal dosing
- renal impairment: no adjustment
- HD: no initial dose adjustment, consider incr. subsequent doses up to 2x usual dose; PD: not defined
Hepatic dosing
- Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined
SRC: NLM .