Skyrizi Dosage

Generic name: risankizumab
Drug class: Interleukin inhibitors

Medically reviewed by  A Ras MD.

 

 Recommended Adult Dosing

Dosage forms:  INJ (auto-injector): 150 mg; INJ (pre-filled syringe): 150 mg per mL; INJ (on-body injector): 360 mg; INJ (vial): various

Special Note

[formulation clarification]
Info: nonproprietary name = risankizumab-rzaa

Psoriasis, mod-severe plaque

[150 mg SC q12wk]
Start: 150 mg SC x1 on wk 0, 4, then q12wk

Psoriatic arthritis

[150 mg SC q12wk]
Start: 150 mg SC x1 on wk 0, 4, then q12wk; Info: use alone or w/ non-biologic DMARDs

Crohn dz, mod-severe

[induction tx]
Dose: 600 mg IV x1 on wk 0, 4, 8
[maintenance tx]
Dose: 360 mg SC q8wk; Start: 4wk after last induction dose

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[Crohn dz]
cirrhosis: caution advised
[all other indications]
hepatic impairment: not define

SRC: NLM .