Signifor Dosage

Generic name: pasireotide
Brand names: Signifor, Signifor LAR
Drug class: Somatostatin and somatostatin analogs

Medically reviewed by A Ras MD.

Recommended Adult Dosing

Dosage forms: INJ: 0.3 mg per mL, 0.6 mg per mL, 0.9 mg per mL

[0.3-0.9 mg SC bid]

Start: 0.6 mg or 0.9 mg SC bid; Info: adjust dose in 0.3 mg increments based on tx response and urinary free cortisol levels

[no adjustment]

renal impairment: no adjustment

HD/PD: no adjustment; no supplement

Child-Pugh Class B: start 0.3 mg bid, max 1.2 mg/day; Child-Pugh Class C: avoid use

SRC: NLM .