Semglee Dosage

Generic name: insulin glargine
Drug class: Insulin

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  INJ (U-100 pen): 100 units per mL; INJ (U-100 vial): 100 units per mL

Diabetes mellitus, type 1

[individualize dose SC qd]

Start: approx. 33% of total daily insulin requirement; Info: usual total daily insulin requirement 0.5-1 units/kg/day (basal + prandial); dose adjustment may be needed during pregnancy and/or immed. postpartum; onset 1h, no true peak, duration 24h (long-acting basal insulin)

Diabetes mellitus, type 2

[individualize dose SC qd]

Start: 0.2 units/kg/dose SC qd up to 10 units/day; Info: dose adjustment may be needed during pregnancy and/or immed. postpartum; onset 1h, no true peak, duration 24h (long-acting basal insulin)

Renal dosing

[see below]

renal impairment: consider decr. usual dose

HD/PD: consider decr. usual dose; no supplement

Hepatic dosing

[adjust dose amount]

hepatic impairment: decr. dose, amount not defined

 Recommended Peds Dosing

Dosage forms:  INJ (U-100 pen): 100 units per mL; INJ (U-100 vial): 100 units per mL

Diabetes mellitus, type 1

[6 yo and older]

Dose: individualize dose SC qd; Start: approx. 33% of total daily insulin requirement; Info: usual total daily insulin requirement 0.5-1 units/kg/day (basal + prandial); onset 1h, no true peak, duration 24h (long-acting basal insulin)

Diabetes mellitus, type 2

[individualize dose SC qd]

Start: 0.2 units/kg/dose SC qd up to 10 units/day; Info: onset 1h, no true peak, duration 24h (long-acting basal insulin)

Renal dosing

[see below]

renal impairment: consider decr. usual dose

HD/PD: consider decr. usual dose; no supplement

Hepatic dosing

[adjust dose amount]

hepatic impairment: decr. dose, amount not defined

SRC: NLM .