Seasonique Dosage

Generic name: ethinyl estradiol and levonorgestrel (extended-cycle)
Drug class: Contraceptives

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  monophasic pack

Contraception

[1 tab PO qd]

Start: 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

*Dysfunctional uterine bleeding, moderate

[acute phase]

Dose: 1 tab PO bid x5-7 days, then 1 tab PO qd until all tabs given in 1 pack; Alt: 1 tab PO tid x3 days or until bleeding subsides, then 1 tab PO bid x3-5 days, then 1 tab PO qd until all tabs given in 1 pack

[maintenance phase]

Dose: 1 tab PO qd; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

*Dysmenorrhea

[1 tab PO qd]

Start: 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

*Emergency contraception

[4 tabs PO q12h x2 doses]

Start: ASAP after unprotected intercourse; maximum efficacy w/in 72h, moderate efficacy w/in 120h; Info: use light blue green tabs (levonorgestrel/ethinyl estradiol 0.15 mg/30 mcg); repeat dose if vomiting occurs w/in 3h

*Endometriosis

[1 tab PO qd]

Start: 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

Renal dosing

[see below]

renal dz: not defined, caution advised

HD/PD: not defined, caution advised

Hepatic dosing

[see below]

active hepatic dz: contraindicated

 Recommended Peds Dosing

Dosage forms:  monophasic pack

Contraception

[postmenarchal females]

Dose: 1 tab PO qd; Start: 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

Dysfunctional uterine bleeding, moderate

[acute phase, postmenarchal females]

Dose: 1 tab PO bid x5-7 days, then 1 tab PO qd until all tabs given in 1 pack; Alt: 1 tab PO tid x3 days or until bleeding subsides, then 1 tab PO bid x3-5 days, then 1 tab PO qd until all tabs given in 1 pack

[maintenance phase, postmenarchal females]

Dose: 1 tab PO qd; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

Dysmenorrhea

[postmenarchal females]

Dose: 1 tab PO qd; Start: 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

Emergency contraception

[postmenarchal females]

Dose: 4 tabs PO q12h x2; Start: ASAP after unprotected intercourse; maximum efficacy w/in 72h, moderate efficacy w/in 120h; Info: use light blue green tabs (levonorgestrel/ethinyl estradiol 0.15 mg/30 mcg); repeat dose if vomiting occurs w/in 3h

Endometriosis

[postmenarchal females]

Dose: 1 tab PO qd; Start: 1st Sunday after onset of menses; Info: D/C >4wk before, restart >2wk after surgery w/ VTE risk; restart >4wk postpartum or >6wk postpartum if breastfeeding

Renal dosing

[see below]

renal dz: not defined, caution advised

HD/PD: not defined, caution advised

Hepatic dosing

active hepatic dz: contraindicated

SRC: NLM .