Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: TAB: 20 mg, 40 mg
Ph-positive CML, chronic phase
- [T315I-negative dz]
- Dose: 80 mg PO daily; Alt: 40 mg PO bid; Info: for pts previously treated with 2 or more TKIs; avoid food for at least 2h before and 1h after admin; do not cut/crush/chew tab
- [T315I-positive dz]
- Dose: 200 mg PO bid; Info: avoid food for at least 2h before and 1h after admin; do not cut/crush/chew tab
- [see below]
- eGFR >15: no adjustment; eGFR <15: not defined
- HD/PD: not defined
- [no adjustment]
SRC: NLM .