Scemblix Dosage

Generic name: asciminib
Dosage form: tablets
Drug class: BCR-ABL tyrosine kinase inhibitors

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  TAB: 20 mg, 40 mg

Ph-positive CML, chronic phase

[T315I-negative dz]

Dose: 80 mg PO daily; Alt: 40 mg PO bid; Info: for pts previously treated with 2 or more TKIs; avoid food for at least 2h before and 1h after admin; do not cut/crush/chew tab

[T315I-positive dz]

Dose: 200 mg PO bid; Info: avoid food for at least 2h before and 1h after admin; do not cut/crush/chew tab

Renal dosing

[see below]

eGFR >15: no adjustment; eGFR <15: not defined

HD/PD: not defined

Hepatic dosing

[no adjustment]

SRC: NLM .