Savella Dosage

 Recommended Adult Dosing

Dosage forms:  TAB: 12.5 mg, 25 mg, 50 mg, 100 mg; convenience pack

Fibromyalgia

[50 mg PO bid]

Start: 12.5 mg PO qd x1 day, then 12.5 mg PO bid x2 days, then 25 mg PO bid x4 days, then 50 mg PO bid; Max: 200 mg/day; Info: taper dose gradually to D/C

Renal dosing

CrCl > 60: no adjustment; CrCl 30-59: not defined, caution advised; CrCl 5-29: decr. usual dose by 50%, max 100 mg/day; ESRD: avoid use

HD/PD: not defined

Hepatic dosing

severe impairment: caution advised; chronic hepatic dz: avoid use