Saquinavir Dosage

Generic name: saquinavir
Brand names: Invirase, Fortovase
Drug class: Protease inhibitors

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  TAB: 500 mg

HIV infection, tx-naive

[1000 mg PO bid]

Start: 500 mg PO bid x7 days; Info: not recommended per DHHS guidelines; give w/ ritonavir 100 mg PO bid; give w/in 2h after full meal; do not crush tab

HIV infection, tx-experienced

[1000 mg PO bid]

Info: not recommended per DHHS guidelines; give w/ ritonavir 100 mg PO bid; give w/in 2h after full meal; do not crush tab

Renal dosing

renal impairment: no adjustment

HD: no adjustment; no supplement; PD: not defined

Hepatic dosing

mild-mod impairment: caution advised; severe impairment: contraindicated

 Recommended Peds Dosing

Dosage forms:  TAB: 500 mg

HIV infection, tx-naive

[>16 yo]

Dose: 1000 mg PO bid; Start: 500 mg PO bid x7 days; Info: not recommended per DHHS guidelines; give w/ ritonavir 100 mg PO bid; give w/in 2h after full meal; do not crush tab

HIV infection, tx-experienced

[>16 yo]

Dose: 1000 mg PO bid; Info: not recommended per DHHS guidelines; give w/ ritonavir 100 mg PO bid; give w/in 2h after full meal; do not crush tab

Renal dosing

[not defined]

renal impairment: consider adult renal dosing for guidance

HD/PD: consider adult renal dosing for guidance

Hepatic dosing

mild-mod impairment: caution advised; severe impairment: contraindicated

SRC: NLM .