Safinamide Dosage

Generic name: safinamide
Brand name: Xadago
Drug class: Dopaminergic antiparkinsonism agents

Medically reviewed by  A Ras MD.

 

 Recommended Adult Dosing

Dosage forms:  TAB: 50 mg, 100 mg

Parkinson dz, adjunct tx

[50-100 mg PO qd]
Start: 50 mg PO qd x2wk, then may incr. to 100 mg PO qd; Max: 100 mg/day; Info: use w/ carbidopa/levodopa; decr. dose to 50 mg/day x1wk to D/C

Renal dosing

[see below]
renal impairment: no adjustment
HD/PD: not defined

Hepatic dosing

Child-Pugh Class B: max 50 mg/day; Child-Pugh Class C: contraindicated

 

SRC: NLM .