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Generic name: semaglutide 

Brand name: Rybelsus

Class of drugs: Incretin mimetics


What is Rybelsus?


Rybelsus (semaglutide) can be utilized in conjunction with exercise and diet to increase blood sugar control in people suffering from the condition type 2 diabetes.

Rybelsus is typically administered when other diabetes drugs have not worked.

Rybelsus is not a treatment for type 1 diabetes.

Rybelsus is sold in a light to white yellow oval-shaped tablet. It can be purchased in three mg, 7mg, and 14mg strength



There is no need to make use of Rybelsus when you have multiple types of endocrine neoplasia (tumors within your glands) as well as an individual or family medical history of medullary thyroid tumors, insulin-dependent diabetes, or ketoacidosis due to diabetes.

Consult your physician immediately If you notice symptoms of thyroid cancer like swelling or a lump on your neck, difficulty swallowing, hoarse voice, or shortness of breath.

Before taking this medication, you must consult your physician.

Rybelsus is not recommended for taking Rybelsus in the event that you are allergic to semaglutide or you suffer from:

  • Multiple endocrine Neoplasia Type 2 (tumors within glands);
  • A personal or family background of medullary thyroid cancer (a kind of Thyroid Cancer) or
  • diabetes ketoacidosis (call your doctor to seek treatment).

To be sure Rybelsus is suitable for you, inform your doctor that you suffer from:

  • A stomach or intestinal problem;
  • pancreatitis;
  • kidney disease or
  • eye issues due to diabetic conditions (retinopathy).

In studies on animals, semaglutide was found to cause thyroid tumors and thyroid cancer. It is not clear if the effects are present in human beings. Talk to your doctor about the potential risk.

Stop taking Rybelsus at least two months prior to when you are planning to become pregnant. Ask your doctor for a more safe medication to use during this period. The control of diabetes is crucial during pregnancy, and so is gaining the appropriate amounts of weight. Even if you’re overweight and losing weight during pregnancy, it could be harmful to the baby who is stillborn.

It is not recommended to breastfeed while taking Rybelsus.

Rybelsus is not recommended for use by anyone less than 18 years old.

What is the best way to use Rybelsus?

Use Rybelsus exactly as directed by your physician. Follow the directions on your prescription label, and review all medication manuals or instructions sheets. Rybelsus is typically prescribed at a low dosage that is gradually increased every four weeks up to 30 days. Follow your doctor’s dosage instructions extremely carefully.

Rybelsus (oral) is consumed by mouth, generally, every day, when you first get up for at minimum 30 mins prior to the time you consume food or drink. Do not exceed 4 8 ounces of water. Suck the tablet completely and don’t chew, crush or tear it.

Consume within 30-60 minutes following having taken Rybelsus.

Take note of all the instructions for use. Consult your physician or pharmacist for help.

Don’t use various brands of semaglutide at the same time.

The blood sugar level can be affected by illness, stress surgical procedures alcohol consumption, eating infrequently.

Low glucose levels (hypoglycemia) can cause you to feel extremely hungry, dizzy, angry, and shaky. To help treat hypoglycemia fast take a snack or drink of crackers, hard candy or raisins, juice of the fruit, and non-diet drinks. Your physician may give you glucagon injections in cases of extreme hypoglycemia.

Inform your doctor if you notice frequent signs of elevated blood sugar (hyperglycemia) such as an increase in thirst or frequent urination. Talk to your doctor about making any changes to your medication or dosage schedule.

Your treatment could comprise exercise, diet and weight management, medical tests, and other medical attention.

It is possible to become dehydrated in long-term illness. Consult your physician if are suffering from vomiting or diarrhea. Also, if consume less food or drink than you normally do.

Keep Rybelsus within its original container within the room at room temperatures, and away from heat and moisture. Keep it out of reach of pets and children.


Dosing information

Usual Adult Dose for Diabetes Type 2:

Oral Tablets:
Initial dosage: 3 mg orally daily for 30 days. After that, 7 mg orally every day
Titration: If further glucose control is required after having received 7 mg a day for a minimum of 30 days, the dose may be increased to 14 mg once every day.
Maintenance dose: 7-14 mg taken orally, once per day
The maximum dosage is 14 mg per day (taking two tablets of 7 mg to reach 14 mg is not advised).

Usual Adult Dose for Cardiovascular Risk Reduction:

Oral Tablets:
Initial dose: 3 mg taken orally every day for 30 days. After that, 7 mg orally every day
Titration: If further glucose control is required after taking 7 mg/day over a minimum of 30 days, it is possible to increase up to 14 mg taken orally per day.
Maintenance dosage: 7 to 14 mg once orally every day
Maximum dosage of 14 mg/day (taking two tablets with 7 mg for the 14 mg dosage is not advised)

If I do not take a dose?

Do not miss the missed dose, and take the subsequent dose according to the same time.

Don’t take more than two dosages of Rybelsus simultaneously.

If I consume too much?

Get medical attention immediately or contact toll-free the Poison Help line at 1-800-222-1222.

The overdose can cause extreme nausea vomiting, nausea, or the blood sugar levels below.

Rybelsus side effects

Take immediate medical care If you are experiencing symptoms that you are experiencing an allergic reaction Rybelsus: hives, itching; dizziness; rapid heartbeats; difficulty breathing, and swelling of your lips, face, and throat.

Contact your doctor immediately If you are suffering from:

  • vision change;
  • strange mood swings and thoughts of harming yourself
  • Heartbeats that pound or flutter in your chest
  • a euphoric feeling, similar to you’re passing out;
  • symptoms of thyroid tumors swelling or lump that is visible in the neck problems swallowing, a voice that is hoarse or feeling tired;
  • signs of pancreatitis – intense pain in your upper stomach, spreading into your back and nausea, with and without vomiting rapid heart rate
  • gallbladder disorders Upper stomach discomfort, fever, clay-colored stool, and jaundice (yellowing of the eyes or skin);
  • Low blood sugar nausea, fatigue in the morning, sweating and irritability. speedy heart rate or feeling nervous;
  • kidney issues swelling, urination less frequently, feeling fatigued or weak or
  • symptoms of stomach flu gastric cramps and vomiting, loss of appetite diarrhea (may be bloody or watery).

Common Rybelsus adverse effects could be:

  • Low blood sugar (in people suffering from Type 2 Diabetes);
  • Heartburn, stomach upset gas, burping, upset stomach, and bloating;
  • nausea stomach pain, vomiting lack of appetite
  • diarrhea, constipation;
  • stomach flu symptoms; or
  • headache, dizziness, tiredness.

This isn’t a complete list of all side effects. other effects may also be present. Contact your physician for advice regarding medical the effects. You can report any side effects to the FDA at 1-800-FDA-1088.


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