Rifapentine Dosage
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: TAB: 150 mg
Tuberculosis, active
- [continuation phase, weekly regimen, non-HIV pts]
- Dose: 10-20 mg/kg/dose PO qwk x18-31wk; Start: after completing initiation phase; Info: admin. by directly observed tx; give w/ isoniazid 900 mg PO qwk; not 1st-line tx; refer to ATS/CDC/IDSA guidelines; give w/ food
- [*complete daily regimen, >40 kg]
- Dose: 1200 mg PO qd x4mo; Info: for susceptible pulmonary infection; admin. by directly observed tx; give w/ moxifloxacin, isoniazid, and pyrazinamide for intensive phase x8wk; give w/ moxifloxacin and isoniazid for continuation phase to complete course; not 1st-line tx; refer to CDC guidelines; give w/ food
Tuberculosis, latent
- [32.1-49.9 kg]
- Dose: 750 mg PO qwk x3mo; Info: for non-pregnant pts; give w/ weekly isoniazid; 1st-line tx; give w/ food
- [>50 kg]
- Dose: 900 mg PO qwk x3mo; Info: for non-pregnant pts; give w/ weekly isoniazid; 1st-line tx; give w/ food
- [*1 month daily regimen]
- Dose: 600 mg PO qd x1mo; Info: for non-pregnant pts; not 1st-line tx; may self-admin; give w/ daily isoniazid; refer to WHO guidelines; give w/ food
Renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
Hepatic dosing
- hepatic impairment: caution advised
SRC: NLM .