Repatha Dosage
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: INJ (SureClick auto-injector): 140 mg; INJ (pre-filled syringe): 140 mg per mL; INJ (Pushtronex on-body injector): 420 mg
Cardiovascular event risk reduction
- [140 mg SC q2wk]
- Alt: 420 mg SC qmo; Info: for pts w/ established CVD
Primary hyperlipidemia, adjunct tx
- [140 mg SC q2wk]
- Alt: 420 mg SC qmo
Heterozygous familial hypercholesterolemia, adjunct tx
- [140 mg SC q2wk]
- Alt: 420 mg SC qmo
Homozygous familial hypercholesterolemia, adjunct tx
- [420 mg SC qmo or 420 mg SC q2wk]
- Start: 420 mg SC qmo, may incr. to 420 mg SC q2wk after 12wk if inadequate response; Info: may start 420 mg SC q2wk if pt on lipid apheresis
Renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
Hepatic dosing
- Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined
SRC: NLM .