Repaglinide Dosage

Generic name: repaglinide (oral)
Brand name: Prandin
Drug class: Meglitinides

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  TAB: 0.5 mg, 1 mg, 2 mg

Diabetes mellitus, type 2

[HbA1c <8% or tx-naive]

Dose: 0.5-4 mg PO 15-30min before each meal; Start: 0.5 mg PO 15-30min before each meal, may double preprandial dose no more frequently than qwk; Max: 4 mg/dose up to 16 mg/day; Info: skip dose if meal skipped

[HbA1c >8% or tx-experienced]

Dose: 0.5-4 mg PO 15-30min before each meal; Start: 1-2 mg PO 15-30min before each meal, may double preprandial dose no more frequently than qwk; Max: 4 mg/dose up to 16 mg/day; Info: skip dose if meal skipped

Renal dosing

[adjust dose amount]

CrCl 20-40: start 0.5 mg before each meal, titrate slowly; CrCl <20: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

hepatic impairment: caution advised, wait longer intervals between dose adjustments

 

SRC: NLM .