Renflexis Dosage

Dosage forms:  INJ

Crohn dz

[5 mg/kg/dose IV q8wk]

Start: 5 mg/kg/dose IV x1 on wk 0, 2, 6; Info: for mod-severe or fistulizing dz; consider D/C if no response by 14wk; may incr. maint. dose to 10 mg/kg/dose IV q8wk if initial response lost; weigh risk/benefit of reinduction tx if maintenance tx interrupted

Ulcerative colitis, mod-severe

[5 mg/kg/dose IV q8wk]

Start: 5 mg/kg/dose IV x1 on wk 0, 2, 6

Rheumatoid arthritis, mod-severe

[3 mg/kg/dose IV q8wk]

Start: 3 mg/kg/dose IV x1 on wk 0, 2, 6; Info: use w/ methotrexate; may incr. dose up to 10 mg/kg/dose IV q8wk or frequency up to q4wk if incomplete response; weigh risk/benefit of reinduction tx if maintenance tx interrupted

Ankylosing spondylitis

[5 mg/kg/dose IV q6wk]

Start: 5 mg/kg/dose IV x1 on wk 0, 2, 6

Psoriatic arthritis

[5 mg/kg/dose IV q8wk]

Start: 5 mg/kg/dose IV x1 on wk 0, 2, 6

Psoriasis, severe chronic plaque

[5 mg/kg/dose IV q8wk]

Start: 5 mg/kg/dose IV x1 on wk 0, 2, 6; Info: if maintenance tx interrupted, restart 5 mg/kg/dose x1, then 5 mg/kg/dose IV q8wk

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

 Recommended Peds Dosing

Dosage forms:  INJ

Crohn dz, mod-severe

[6 yo and older]

Dose: 5 mg/kg/dose IV q8wk; Start: 5 mg/kg/dose IV x1 on wk 0, 2, 6; Info: consider D/C if no response by 14wk; weigh risk/benefit of reinduction tx if maintenance tx interrupted

Ulcerative colitis, mod-severe

[6 yo and older]

Dose: 5 mg/kg/dose IV q8wk; Start: 5 mg/kg/dose IV x1 on wk 0, 2, 6

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .