Procysbi Dosage
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: DR CAP: 25 mg, 75 mg; DR GRANULE: 75 mg per pkt, 300 mg per pkt
Restricted Distribution in US
Nephropathic cystinosis
- [initial tx]
- Dose: 1300 mg/m^2/day PO/GT divided q12h; Start: 200-300 mg/m^2/day PO/GT divided q12h, then may incr. dose over 4-6wk; Max: 1950 mg/m^2/day; Info: give >30min before or >2h after meals; avoid admin. w/ high fat meal; may open cap; do not crush/chew cap contents or granules; adjust dose by 10% to maintain WBC cystine level <1 nmol ½ cys/mg protein
- [conversion from IR form]
- Dose: 1300 mg/m^2/day PO/GT divided q12h; Max: 1950 mg/m^2/day; Info: give >30min before or >2h after meals; avoid admin. w/ high fat meal; may open cap; do not crush/chew cap contents or granules; adjust dose by 10% to maintain WBC cystine level <1 nmol ½ cys/mg protein
Renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
Hepatic dosing
- [not defined]
SRC: NLM .