Procarbazine Dosage

Generic name: procarbazine
Brand name: Matulane
Drug class: Miscellaneous antineoplastics

Medically reviewed by  A Ras MD.

 

 Recommended Adult Dosing

Dosage forms:  CAP: 50 mg

Hodgkin lymphoma, advanced

[monotherapy]
Dose: 1-2 mg/kg/day PO divided qd-bid; Start: 2-4 mg/kg/day PO divided qd-bid x7 days, then 4-6 mg/kg/day PO divided qd-bid until maximum response, then 1-2 mg/kg/day PO divided qd-bid
[combo tx]
Dose: 100 mg/m^2/dose PO qd on days 1-14 of each cycle

Renal dosing

[not defined]
renal impairment: not defined
HD/PD: not defined

Hepatic dosing

[not defined]
hepatic impairment: caution advised

 

SRC: NLM .