Prevymis Dosage

Generic name: letermovir (oral/injection)
Drug class: Miscellaneous antivirals

Medically reviewed by A Ras MD.

Recommended Adult Dosing

Dosage forms: TAB: 240 mg, 480 mg; INJ: various

[480 mg PO/IV qd until 100 days post-transplant]

Start: between days 0 and 28 of transplant; Info: for CMV seropositive recipients; switch to PO form when possible

[PO route]

CrCl >10: no adjustment; CrCl <10: not defined

HD/PD: not defined

[IV route]

CrCl >50: no adjustment; CrCl <50: not defined, caution advised; Info: PO route preferred due to accumulation of toxic IV vehicle

HD/PD: not defined

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: avoid use

SRC: NLM .