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Prepidil Dosage

Generic name: dinoprostone topical
Brand names: Cervidil, Prepidil, Prostin E2
Drug class: Uterotonic agents

Medically reviewed by  A Ras MD.


 Recommended Adult Dosing

Dosage forms:  GEL: 0.5 mg per applicatorful

Cervical ripening

[0.5 mg PV endocervical]
Max: 1.5 mg/24h; Info: may repeat q6h x2 doses; use 20 mm endocervical cath. if no effacement; use 10 mm cath. if >50% effacement; warm to room temp prior to insertion; remain supine x15-30min

Renal dosing

renal impairment: not defined, caution advised
HD/PD: not defined

Hepatic dosing

[not defined]
hepatic impairment: caution advised


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