Praluent Dosage
Recommended Adult Dosing
Dosage forms: INJ (pen): 75 mg per mL, 150 mg per mL
Primary hyperlipidemia, adjunct tx
- [75 mg SC q2wk]
- Max: 150 mg q2wk; Alt: 300 mg SC q4wk; Info: may incr. dose to 150 mg SC q2wk after 4-8wk
Heterozygous familial hypercholesterolemia, adjunct tx
- [75 mg SC q2wk]
- Max: 150 mg q2wk; Alt: 300 mg SC q4wk; Info: may incr. dose to 150 mg SC q2wk after 4-8wk; give 150 mg SC q2wk if LDL apheresis
Homozygous familial hypercholesterolemia, adjunct tx
- [150 mg SC q2wk]
Cardiovascular event risk reduction
- [75 mg SC q2wk]
- Max: 150 mg q2wk; Alt: 300 mg SC q4wk; Info: may incr. dose to 150 mg SC q2wk after 4-8wk
Renal dosing
- mild-moderate impairment: no adjustment; severe impairment: not defined
- HD/PD: not defined
Hepatic dosing
- mild-moderate impairment: no adjustment; severe impairment: not defined
SRC: NLM .