Pomalyst Dosage
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: CAP: 1 mg, 2 mg, 3 mg, 4 mg
Restricted Distribution in US
Special Note
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments
Multiple myeloma, relapsed or refractory
- [4 mg PO qd on days 1-21 of 28-day cycle]
- Info: for pts who have received at least 2 prior tx, incl. lenalidomide and a proteasome inhibitor, and w/ dz progression on or w/in 60 days after last tx; use w/ dexamethasone +/- elotuzumab, daratumumab, daratumumab/hyaluronidase, or isatuximab; do not open cap
Kaposi sarcoma
- [5 mg PO qd on days 1-21 of 28-day cycle]
- Info: for pts w/ HIV-negative dz or AIDS-related dz after HAART failure; do not open cap
Renal dosing
- [multiple myeloma]
- renal impairment: not defined
- HD: 3 mg PO qd, on dialysis days admin. after dialysis; no supplement; PD: not defined
- [Kaposi sarcoma]
- renal impairment: not defined
- HD: 4 mg PO qd, on dialysis days admin. after dialysis; no supplement; PD: not defined
Hepatic dosing
- [multiple myeloma]
- Child-Pugh Class A or B: 3 mg PO qd; Child-Pugh Class C: 2 mg PO qd
- [Kaposi sarcoma]
- Child-Pugh Class A, B or C: 3 mg PO qd
SRC: NLM .