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Polivy Dosage

Generic name: polatuzumab vedotin
Drug class: Miscellaneous antineoplastics

Medically reviewed by  A Ras MD.


Recommended Adult Dosing

Dosage forms:  INJ

Diffuse large B-cell lymphoma, relapsed or refractory

[1.8 mg/kg/dose IV x1 on day 1 of 21-day cycle]
Info: give x6 cycles; give HSV, PCP prophylaxis during tx; part of multi-drug chemo regimen

Renal dosing

CrCl >30: no adjustment; CrCl <30: not defined
HD/PD: not defined

Hepatic dosing

AST or ALT 1.1-2.5x ULN or bilirubin 1.1-1.5x ULN: no adjustment; AST or ALT >2.5x ULN or bilirubin >1.5x ULN: avoid use



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