Polivy Dosage
Generic name: polatuzumab vedotin
Drug class: Miscellaneous antineoplastics
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: INJ
Diffuse large B-cell lymphoma, relapsed or refractory
- [1.8 mg/kg/dose IV x1 on day 1 of 21-day cycle]
- Info: give x6 cycles; give HSV, PCP prophylaxis during tx; part of multi-drug chemo regimen
Renal dosing
- CrCl >30: no adjustment; CrCl <30: not defined
- HD/PD: not defined
Hepatic dosing
- AST or ALT 1.1-2.5x ULN or bilirubin 1.1-1.5x ULN: no adjustment; AST or ALT >2.5x ULN or bilirubin >1.5x ULN: avoid use
SRC: NLM .