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Plerixafor Dosage

Generic name: plerixafor
Brand name: Mozobil
Drug classes: Hematopoietic stem cell mobilizer, Other immunostimulants

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ: 20 mg per mL

Hematopoietic stem cell mobilization

[<83 kg]
Dose: 20 mg SC qd up to 4 days; Start: after 4 days G-CSF tx; Alt: 0.24 mg/kg/dose SC qd up to 4 days starting after 4 days G-CSF tx; Info: in combo w/ G-CSF; give 11h prior to apheresis
[>83 kg]
Dose: 0.24 mg/kg/dose SC qd up to 4 days; Start: after 4 days G-CSF tx; Max: 40 mg/day; Info: in combo w/ G-CSF; give 11h prior to apheresis

Renal dosing

[<83 kg]
CrCl <50: 13 mg or 0.16 mg/kg/dose qd
HD/PD: not defined
[>83 kg]
CrCl <50: 0.16 mg/kg/dose qd; max 27 mg/day
HD/PD: not defined

Hepatic dosing

[not defined]
SRC: NLM .

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