Plerixafor Dosage

Recommended Adult Dosing

Dosage forms:  INJ: 20 mg per mL

Hematopoietic stem cell mobilization

[<83 kg]

Dose: 20 mg SC qd up to 4 days; Start: after 4 days G-CSF tx; Alt: 0.24 mg/kg/dose SC qd up to 4 days starting after 4 days G-CSF tx; Info: in combo w/ G-CSF; give 11h prior to apheresis

[>83 kg]

Dose: 0.24 mg/kg/dose SC qd up to 4 days; Start: after 4 days G-CSF tx; Max: 40 mg/day; Info: in combo w/ G-CSF; give 11h prior to apheresis

Renal dosing

[<83 kg]

CrCl <50: 13 mg or 0.16 mg/kg/dose qd

HD/PD: not defined

[>83 kg]

CrCl <50: 0.16 mg/kg/dose qd; max 27 mg/day

HD/PD: not defined

Hepatic dosing

[not defined]