Photofrin Dosage
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: INJ
Esophageal CA, palliative tx
- [2 mg/kg/dose IV x1]
- Info: to complete 2-step photodynamic tx (PDT) use laser light 40-50h post-injection, may repeat laser light 96-120h post-injection; may repeat 2-step PDT after >30 days, up to 3 courses total
Endobronchial non-small cell lung CA
- [microinvasive dz]
- Dose: 2 mg/kg/dose IV x1; Info: for pts ineligible for surgery or XRT; to complete 2-step photodynamic tx (PDT) use laser light 40-50h post-injection, may repeat laser light 96-120h post-injection; may repeat 2-step PDT after >30 days, up to 3 courses total
- [palliative tx]
- Dose: 2 mg/kg/dose IV x1; Info: to complete 2-step photodynamic tx (PDT) use laser light 40-50h post-injection, may repeat laser light 96-120h post-injection; may repeat 2-step PDT after >30 days, up to 3 courses total
Barrett esophagus dysplasia, high-grade
- [2 mg/kg/dose IV x1]
- Info: for pts ineligible for esophagectomy; to complete 2-step photodynamic tx (PDT) use laser light 40-50h post-injection, may repeat laser light 96-120h post-injection; may repeat 2-step PDT after >90 days, up to 3 courses total
Renal dosing
- renal impairment: not defined, caution advised
- HD/PD: not defined, caution advised
Hepatic dosing
- [not defined]
- hepatic impairment: caution advised
SRC: NLM .