Percocet Dosage

Generic name: acetaminophen and oxycodone
Drug class: Narcotic analgesic combinations

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 2.5 mg/325 mg, 5 mg/325 mg, 7.5 mg/325 mg, 10 mg/325 mg

Pain, moderate-mod. severe

[2.5-10 mg oxycodone PO q6h prn]
Info: use lowest effective dose, shortest effective tx duration; q4h dosing may be needed if severe pain or opioid-tolerance; do not exceed 1 g/4h and 4 g/day acetaminophen from all sources; taper dose gradually to D/C if long-term use

Renal dosing

[see below]
renal impairment: titrate slowly
HD/PD: not defined

Hepatic dosing

[not defined]
hepatic impairment: caution advised

Recommended Peds Dosing

Dosage forms:  TAB: 2.5 mg/325 mg, 5 mg/325 mg

Pain, moderate-mod. severe

[>16 kg]
Dose: 0.05-0.15 mg/kg oxycodone PO q6h prn; Max: 5 mg/dose oxycodone; Info: use lowest effective dose, shortest effective tx duration; q4h dosing may be needed if severe pain or opioid-tolerance; do not exceed 75 mg/kg/day up to 1 g/4h and 4 g/day acetaminophen from all sources; taper dose gradually to D/C if long-term use

Renal dosing

[not defined]
renal impairment: consider adult renal dosing for guidance
HD/PD: consider adult renal dosing for guidance

Hepatic dosing

[not defined]
hepatic impairment: caution advised

SRC: NLM .