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Peramivir Dosage

Generic name: peramivir
Brand name: Rapivab
Dosage form: intravenous solution (10 mg/mL)
Drug class: Neuraminidase inhibitors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ

Influenza A and B (seasonal flu) tx, uncomplicated

[600 mg IV x1]
Start: w/in 48h of sx onset

Renal dosing

[adjust dose amount]
CrCl 30-49: 200 mg x1; CrCl 10-29: 100 mg x1; CrCl <10: not defined
HD: 100 mg x1, on dialysis days admin. after dialysis; no supplement; PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  INJ

Influenza A and B (seasonal flu) tx, uncomplicated

[6 mo-12 yo]
Dose: 12 mg/kg/dose IV x1; Start: w/in 48h of sx onset; Max: 600 mg/dose
[13 yo and older]
Dose: 600 mg IV x1; Start: w/in 48h of sx onset

Renal dosing

[6 mo-1 yo]
CrCl <50: not defined, caution advised
HD/PD: not defined, caution advised
[2-12 yo]
CrCl 30-49: 4 mg/kg/dose x1, max 600 mg/dose; CrCl 10-29: 2 mg/kg/dose x1, max 600 mg/dose; CrCl <10: not defined, caution advised
HD/PD: not defined, caution advised
[13 yo and older]
CrCl 30-49: 200 mg x1; CrCl 10-29: 100 mg x1; CrCl <10: not defined
HD: not defined, consider adult renal dosing for guidance; PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .

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