Pentobarbital Dosage

Dosage forms:  INJ

Procedural sedation

[150-200 mg IM x1]

Info: onset 10-15min IM, duration 1-4h IM

Barbiturate coma

[1-3 mg/kg/h IV]

Start: 10-15 mg/kg/dose IV x1, then 1 mg/kg/h IV; Info: taper dose gradually to D/C if long-term use

Renal dosing

[adjust dose amount]

renal impairment: decr. usual dose, amount not defined

HD/PD: not defined

Hepatic dosing

[adjust dose amount]

hepatic impairment: decr. usual dose, amount not defined

Recommended Peds Dosing

Dosage forms:  INJ

Procedural sedation

[2-6 mg/kg/dose IM x1]

Max: 100 mg/dose; Alt: 1-3 mg/kg/dose IV x1; Info: onset 10-15min IM, 1min IV; duration 1-4h IM, 15min IV

Barbiturate coma

[1-3 mg/kg/h IV]

Start: 10-15 mg/kg/dose IV x1, then 1 mg/kg/h IV; Info: taper dose gradually to D/C if long-term use

Renal dosing

[adjust dose amount]

renal impairment: decr. usual dose, amount not defined

HD/PD: not defined

Hepatic dosing

[adjust dose amount]

hepatic impairment: decr. usual dose, amount not defined